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Alzheimer ’s disease is a reform-minded neurodegenerative disease that demolish a someone ’s memory and cognitive function . The condition damages the brain prison cell connections , causing the cells to degenerate and die , thus destroy retention and other related mental functions . Confusion and memory loss are the chief symptoms of this condition , and there is , as of yet , no cure for Alzheimer ’s disease . There has been a lot of argumentation on what is the exact causal agent of Alzheimer ’s disease , with new research suggesting that moderate to severe traumatic genius accidental injury can increase the risk of Alzheimer ’s in many people . Concussion resulting from brainiac injury has been link up to brain changes in people who are at risk for Alzheimer ’s . Read on to find out more about can a concussion cause Alzheimer ’s disease .
Can a Concussion Cause Alzheimer’s Disease?
Alzheimer ’s diseaseis a progressive neurodegenerative disorder that destroys brain cells and get deprivation of memory and other critical mental functions.(1,2)Alzheimer ’s disease is know to be the most common cause of dementia , in which a individual experiences a gradual decline in their behavioural , thinking , and societal skills.(3)The stipulation disrupts a person ’s ability to survive independently . The status is believed to be get by an abnormal build - up of sure toxic proteins in and around the brain cells.(4,5 )
While the precise cause of Alzheimer ’s disease is not screw , but many research worker always suspected that restrained to life-threatening brain injury was a known risk of exposure factor for conditions that affect the genius , such as Alzheimer ’s disease . Now , a new report has linked concussion and an increase endangerment of inherited endangerment for Alzheimer ’s .
Research from the Boston University School of Medicine ( BUSM ) report that their study showed promise of detecting the wallop of a concussion on neurodegeneration.(6)The study has been published in the diary Brain .
This inquiry follows in the footsteps of several other work that have link up mild to severe traumatic brain hurt or concussion to dementia.(7 )
Alzheimer ’s disease assail the encephalon cells and tends to worsen with time . As mentioned above , Alzheimer ’s is the most vulgar figure ofdementia , which is an umbrella term used for diseases that result to a declivity of a person ’s mental faculties.(8,9)Over meter , mental deterioration becomes severe enough to get down interpose with day to day life-time .
Alzheimer ’s disease is one of the leading crusade of expiry worldwide and in the United States , which can neither be prevented nor cured.(10)It is estimated that over five million masses in the US alone endure with Alzheimer ’s disease , and this number is only expect to develop exponentially in the come years as the infant boomer coevals start up participate the eld of 65 and over.(11 )
The study carried out by BUSM noted that moderate to severe traumatic brainiac hurt had been established as being the strongest environmental risk divisor for developing late - onset Alzheimer ’s and other forms of dementedness or neurodegenerative disorder . However , it is still unclear if the risk is the same for mild traumatic brain wound , which the research team need to find.(12 )
Looking at the Research
The inquiry team looked at 160 war veterans who were in the eld radical of 19 to 58 years and had served in Afghanistan and Iraq . Many of these veterans were diagnosed with soft traumatic mind injury and hadpost - traumatic accent disorder(PTSD).(13 )
The participants were all givenMRI scanfrom which the researchers took mensuration of the thickness in the cortical brain neighborhood . These regions are make out to show impairment in the early stage of Alzheimer ’s disease . The measurements from the cortical brain part were then compare with measurements taken from restraint regions .
At the same time , researchers also calculate the genetic risk score for Alzheimer ’s for each player . This was done by equate results from the participants ’ genotype mental testing with info on mellow - risk factor taken from a larger Alzheimer ’s disease genome study.(14 )
The results showed that concussion or a balmy traumatic brain injury had a significant influence on the genetic risk for produce Alzheimer ’s disease . This link has been established between the cortical thickness and the genetic risk for Alzheimer ’s disease . participant who had a high genic risk and had suffered a concussion were get to have decreased cortical heaviness in the regions of the brain that are discover as being susceptible to Alzheimer ’s disease.(15 )
At the same time , the investigator also found that the cortical thinning in the Alzheimer ’s vulnerable region in the brain had a purpose to play in the reduce memory board performance .
As a result , the researchers recommend that there is a indigence for people to keep a platter of even mild head injuries because if there is a genetical risk for Alzheimer ’s already present , then these mild head injuries may go on to become long - term wellness problems , including brain disease .
Conclusion
A new research subject field has found that experiencing a concussion , even a soft one , can increase the peril of developing Alzheimer ’s disease if you already have a genetic risk to the disease . It was antecedently known that a moderate to severe traumatic brain injury increases your risk of developing dementia , even up to 30 class after the harm .
However , this newfangled field has also shown that even a meek traumatic combat injury to the brain can increase the peril of developing Alzheimer ’s at an Old age .
The results of this study have foreground the grandness of properly documenting any concussion issue , no matter how minor you feel they are . Also , make a musical note of their symptoms , even if you simply think that it took you a turn longer to ‘ shake it off . ’ The investigator hope to diffuse awareness about the dangers of take a concussion and how any type of injury to the brain can prove to be dangerous in the future . The study also shows promise in helping physician notice any potential mind impairment that a concussion might inflict in the early twelvemonth itself . However , more research is still needed to look at the accurate mechanism that accelerate the deterioration of the brain after a concussion .
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