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Inflammation of the muscularity is known as myositis.1The cause of myositis is many prominent being the infections . infection admit viral , bacterial and parasitic contagion . The computer virus induce myositis through the various mechanism of action . Myositis damages the molecular social organisation of the muscles and musculus fibers . The symptom of myositis admit weakness , pain , and stiffness of the brawniness .
Can A Virus Attack Your Muscles?
onset by the computer virus on the muscles and cause inflammation is jazz as viral myositis.2Viral myositis result in the damage to muscle fibers and release or revision in the physiological function of muscle .
The symptom experienced by the patient suffer from viral myositis include muscle weakness , warmheartedness , and pain due to stiff muscles . Although coarse in all age groups , the virus ordinarily attack children plausibly due to the unripened muscle prison cell . preponderance of the disease is more in Male as compared to females .
During the viral myositis , serum creatine kinase is advance and the muscle biopsy reveals devolution of musculus fibers with the leukocyte infiltration and muscle necrosis .
Viral myositis may be subacute , acute or chronic . While acute and sub - acute myositis is in the main ego - limiting and the condition subside within a few days , chronic form of the disease require medications and is the result of chronic viral transmission which has progressed to muscles . Some cases of viral myositis may cause rhabdomyolysis .
The virus affects the muscle to induce myositis mainly through two different chemical mechanism :
Direct Infection . In these cases , the virus now affects the muscles result in disruption of the muscular social organization .
lighting . Whenever any foreign particles such as virus enter the body , it triggers the immune system . The resistant system free inflammatory mediators in reply to the virus or other foreign particles . The inflammation may reach to the muscle causing myopathy .
Other mechanism through which a computer virus make myositis include molecular mimicry , and tenacious infections .
It has also been seen that the treatment of patients through antiretroviral drug may also ensue in myositis ; Antiretroviral drugs such as AZT functions by stamp down the viral DNA polymerase and help oneself in managingHIVinfection . However , during the process , these drug also inhibit various critical enzymes of the human cells such as DNA polymerase beta and mitochondrial DNA polymerase da Gamma . This results in the inhibition of human mitochondrial DNA comeback leading to a reduction in oxidative phosphorylation . Disturbance in oxidative phosphorylation results in the establishment of active O species and increase oxidative stress . This results in reduced energy yield in muscles leading to muscle pain and weakness in muscles .
Calf muscle painful sensation is most vernacular in child recover from a viral illness . The experimental condition was term as myalgia cruris epidemics by Lundeberg in 1957 . The Benign Acute Childhood myositis is a non - serious self - limiting consideration for which no specific treatment such as antiviral therapy is require .
The computer virus which has the voltage to cause myositis includes Cytomegalovirus , Epstein Barr Virus , adenovirus , influenza A and B , parainfluenza , herpes simplex , and Coxsackie . The viral myositis has natural recuperation and does not command any discussion however in some casing life history - threatening complications such as keen renal failure , cardiac cardiac arrhythmia , rhabdomyolysis , myoglobinuria , and compartment syndrome may lead to meaning morbidity . Among the myositis do virus , most cases are stimulate by influenza A and Influenza B computer virus . Studies indicate that influenza vitamin B complex is more potent in causing myositis as equate to influenza A virus . This is due to the fact that grippe B virus has a unique NB protein present in its membrane that help in viral launching and is all related to to myotrophic properties .
Conclusion
Viral myositis is caused either through the direct attack of the virus on muscles or the resistant system causes inflammation of the muscles . Viral culture from the muscles is unsuccessful however ; the increased layer of creatinine kinase indicates muscle degeneracy . Although the condition is self - limiting and does not require any treatment however , some case of myositis onward motion to develop rhabdomyolysis , renal failure or cardiac cardiac arrhythmia .
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