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Topic Overview
Researchers at the University of Wurzburg have derive up with a surprising disclosure that the HHV-6 computer virus of the herpes virus family has the potentiality to cause bipolar disorder . The virus does this by affecting the neuron which leads to cognitive impairments resulting in various psychiatric illnesses . The HHV-5 virus impact the Purkinje cells , which is a vital part of the cerebellum . The cerebellum trifle an crucial part in musculus control , balance , and posture of an individual . It also is pivotal in influencing memory , voice communication , and emotion of a person . The researchers at the University of Wurzburg come up with startling revelations as to how these Purkinje cadre were vulnerable to various infections , especially with human herpes computer virus or HHV-6[1 ] .
This was specially seen in people with a sleep with diagnosis ofbipolar disorderordepression . The National Institute of Mental Health say that about 5 % of the common population in United States had had bipolar disorder at some point or the other[1 ] .
Additionally , approximately 6 % of all grownup in the United States experience at least a solitary sequence of depression at some point in their life . This clause gives an overview of the contingent of the sketch and explains how Herpes Virus can stimulate bipolar disorderliness by regard the neurons in the brain[1 ] .
Can Herpes Virus Cause Bipolar Disorder?
The base cause of bipolar disorder still rest a closed book , there is a loyal belief among researchers that both environmental and genetic science wager an crucial use in the development of this condition . As an example , a recent field of study done on bipolar disorder identified around 40 + gene mutations that potentially increased the risk of infection of depression in an individual well and another subject hint that around 80 % of the overall risk for schizophrenic psychosis in the great unwashed can be due to genetic abnormalities[2 ] .
A latest research has spill more ignitor on the persona that environmental factors , especially viruses , play in the development of modality disorders like bipolar disorder . This has been highlighted in the journal Frontiers of Microbiology . A team of research worker led by Dr. Prusty from the department of Microbiology at the University of Wurzburg in Germany found out that mass who had bipolar upset or depressive symptoms had their nerve cell promise Purkinje cell being infected by the HHV-6 virus . These neuron are found in the cerebellum and influence as to how an person feel . It also hold the posture , balance , and motor function of the body[2 ] .
The cerebellum also is involved with cognition , language , and mood of an individual . The question now arises how HHV-6 virus cause bipolar disorder . For this , Dr. Prusty conducted two gravid age bracket of brain biopsy . The biopsy revealed that there were active HHV infections in the Purkinje cadre of people who had depressive and bipolar disorder . Certain inherited factors have always been cognise to increase the hazard of various psychiatric precondition like depressive disorderliness and dementia praecox along with bipolar disorder[2 ] .
In this latest study , it is now base that environmental factor like human herpes virus can also cause neural inflammation very early in life . These virus interfere with the normal development of nerve cell and the overall immune system of the body at vital microscope stage of maturation of an individual . Dr. Prusty adds on that the study clear indicates a stark contraindication that viruses that were consider to be dormant in various organs and tissue paper of the body do not cause any harm to the overall health of an individual in the long term[2 ] .
Dr. Prusty also advert that there is increase evidence that the human herpes computer virus is also responsible for various other neurological condition . Studies have identified that the HHV-6A and HHV-7 are lie with to increase the risk of stimulate Alzheimer disease . Studies conducted on the brain of people who have had these disease have shown them to be infect with these viruses[2 ] .
In the coming days , the research team lead by Dr. Prusty is be after to study the molecular chemical mechanism that can give information as to how these computer virus damage the Purkinje cells causing bipolar disorder and other psychiatrical conditions[2 ] .
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