Can I Give Aspirin to My 16 Year Old?
Do children and teenager have a cause - effect relationship between the utilisation of St. Joseph ( acetylsalicylic acid ) and Reye syndrome ? The wellness authorities seem to call up so . The scientific residential area does not see the matter so distinctly .
In Great Britain , the geezerhood reach which is nix from consumption of acetylsalicylic acid has been increased from 12 to 16 years of long time .
In Spain , since 1987 , the prospectuses of the fit containers admit the recommendation to confab the Doctor of the Church before the supplying of aspirin to children and teen in cases of fever , flu orchickenpox . It is also recommend that the doctor should be look up straight off if vomiting or lethargy occurs after antipyretic use .
moreover , lately the Committee on the Safety of Medicines has recommended that babe aspirin passes from advertising pharmaceutical strong suit to being a product sell only by prescription . In the USA , for market the St. Joseph , safety container that prevent their first step by children must be used and the warning of the possible relationship between drug andReye syndromemust be included .
In 1963 , Dr. R.D.K. Reye at the hospital in Sydney , Australia , analyzed for the first time , in children , the being of an piercing , non - incendiary encephalopathy syndrome . Some previous descriptions in the medical literature appeared since 1929 , but it was Dr. Reye ’s study that allowed an precise diagnosing of the syndrome that received his name .
The etiology of the syndrome is , to a large extent , nameless and ordinarily occurs in children after suffering a viral infection ( upper respiratory tract , grippe , chicken syphilis or gastroenteritis ) lead off the symptom with disgorgement , sleepiness and lethargy accompany by an discriminating non - inflammatory brain disease that can impact the spirit level of cognisance . Hepatic dysfunction that causes a large increment in plasma transaminase and ammonia also ordinarily occurs .
The disease is rare but has a high mortality . Its oftenness is of the order of 0.03 - 1 per one hundred thousand new people up to 18 years old with a high fatality rate of up to 50 % a few years ago , which has been reduced to 25 % today as a result of an earlier diagnosis and use of more aggressive therapies . The high relative incidence is around 7 old age old and is already extremely uncommon in newborn infant or 18 class olds . It is very authoritative that in almost all the known case the patients antecedently , in the three old weeks , had suffered some viral infection .
It is presently thought that Reye syndrome act a sudden sound failure of the functioning of the mitochondria , preceded by an intense viral prodromal phase , with induction of various types : toxins , drugs , metabolic diseases …
From the first Reye´s verbal description , it began to seem indications of an association of the syndrome with the consumption of aspirin , being in the bibliography more than half dozen of epidemiologic study that bear that idea .
An important American wellness organization , said in a report that , of 17 nestling diagnosed with the syndrome , 12 had a relationship with Bayer and only 5 lack it and their eld was higher than 18 years . A more quantitative research , the Yale Multicenter Study , also base a drug - core human relationship , deducting the value of 35 for the computation of relative risk .
In a late publication of the New England Journal of Medicine it is highlighted that the moment of the forsaking of aspirin as antifebrile medicine in children has been the decrease in the relative incidence of the syndrome . In fact , in the United States of America , the growth in shell occurred towards the first of the 1970s , and since then a gradual and uninterrupted decrease has withdraw station , something that has also pass in other countries such as Australia .
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