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What is Clinically Isolated Syndrome (CIS)?
Clinically isolate syndrome ( CIS ) is an episode of neurologic symptoms that hold up for 24 hours and is associated with fever , infection , and otherillnesses . It involves demyelination ( loss of myeline , protective coat of the mettle cellular phone ) in the central nervous system .
Clinically isolated syndrome ( CIS ) is often categorized as a type of multiple sclerosis , as its first clinical episode . There are a few chance of a clinically isolate syndrome evolve into multiple sclerosis.(1 )
How are Clinically Isolated Syndrome and Multiple Sclerosis Different from Each Other?
The major divergence is that Clinically set apart syndrome ( CIS ) is a exclusive episode while multiple sclerosis involves multiple episode or flare - ups .
Once happen , there is no surety that Clinically isolated syndrome ( CIS ) will take place again . Multiple induration is a womb-to-tomb illness with no cure . There can only be symptom management .
Conditions associated with Clinically sequestrate syndrome ( CIS ) include :
Clinically isolate syndrome ( CIS ) can lead to trouble with equipoise and coordination , dizziness while walking , sexual dysfunction , muscle stiffness or spasticity , and difficultness in walking .
In both Clinically keep apart syndrome ( CIS ) and multiple sclerosis there is scathe to the myelin sheath . Symptoms depend on the location of the wound .
It is difficult to differentiate between the two and can be detected through an MRI . If there is evidence of a single installment it is Clinically isolated syndrome ( CIS ) . If multiple lesions and episodes are detect a somebody may have multiple sclerosis .
Causes of Clinically Isolated Syndrome
There is an inflammation and damage of the medulla sheath in Clinically keep apart syndrome ( CIS ) that occurs anywhere in the key neural system of rules .
The exact case is not decipherable , but there are sure risk factor associate with its occurrence .
An episode of Clinically isolated syndrome ( CIS ) assign a person at risk of developing multiple sclerosis .
How to Diagnose Clinically Isolate Syndrome?
If any symptom of Clinically insulate syndrome ( CIS ) is noticed the physician refers the patient to a brain doctor .
The neurologist takes a consummate medical history and does an examination of :
There are a few diagnostic tests that are advised , that include :
Clinically Isolated Syndrome Progression to Multiple Sclerosis
It is not necessary every Clinically isolated syndrome progresses tomultiple sclerosis .
If an MS - like brain lesion is observe in MRI there are 60 - 80 percent chances of having another solar flare - up and multiple sclerosis as a diagnosis in several years.(1 )
If no MS - like brain wound is detected the fortune of developing multiple sclerosis is only 20 % .
According to a reputation on the rude trend of Clinically isolated syndrome:(3 )
As a person has a second episode the doc advises another MRI .
Treatment of Clinically Isolated Syndrome
A mild cause of Clinically isolated syndrome clears up on its own within a point of few weeks .
In case of a serious symptom ofoptic neuritis , a mellow dose of steroid is give , which is either injected or given by word of mouth . sex hormone hasten the recuperation .
There are numerous disease - modifying drugs that are used in multiple induration . They help reduce the severity and frequency of flare - ups .
They are legion drug that are O.K. for the handling of Clinically detached syndrome . It is good to address with a brain doctor about the benefits and peril of each before starting them .
