Carisoprodol ( Soma ) also known as Soprodal and Vanadom . Soma is a chemical compound of carisoprodol with codeine and aspirin ( containing Aspirin , Carisoprodol , and Codeine ) .
Chemistry - Chemically , carisoprodol is N - isopropyl-2 - methyl-2 - propyl-1 , 3 - propanediol dicarbamate and the molecular formula is C12H24N2O4 , with a molecular weightiness of 260.33 . White crystalline powder . Soluble in alcoholic drink , chloroform and acetone .
Taste of Carisoprodol ( Soma)-Bitter .
How Does Carisoprodol (Soma) Work?
The chemical mechanism of action mechanism is not understandably specify . Carisoprodol modulate neurotransmitter activities in spinal corduroy and reticular formation in brain . enquiry has not shown any change in brawn actin myosin activities in muscles .
Prescription - Carisoprodol is usable as whitened tablets .
Carisoprodol Dosage - Tablet strength is 250 atomic number 12 or 350 mg , dosage is double or three time a daylight . Dose depends on altitude , weight and tolerance .
Prescription Duration - Carisoprodol ( Soma ) is usually prescribed for 3 months duration , long - term benefit is not established . In some patients withcerebral palsyand severe daily spasm if other brawn relaxants are not beneficial and carisoprodol is efficacious then treatment is carry on for draw out flow with careful observations for side effects .
Storage - show pharmacy teaching on feeding bottle . stash away on ledge at room temperature , strictly follow expiratory date .
concentration - Carisoprodol is absorbed by intestinal mucosa and heyday plasma assiduousness was celebrate after 1.5 to 2 hours . Bioavailability is not known .
Metabolism - Carisoprodol is metabolized by cytochrome enzyme CYP2C19 to form meprobamate inliver .
Elimination of Carisoprodol (Soma)
Carisoprodol is eliminated by both renal and non - renal route like sweat and bosom milk . evacuation half - life of about 2 hour . Elimination ½ living of metabolite meprobamate is just about 9 to 10 hour . flesh is pass bykidney . Concentration of carisoprodol and meprobomate is high at toxic grade in - patient with renal failure . Carisoprodol is dialyse and decimate by haemodialysis and peritoneal dialysis .
Hepatic Elimination : patient role with Reduced CYP2C19 action
SOMA ( carisoprodol ) should be used with caveat in patients with liver disease and low CYP2C19 activity . The safety and pharmacokinetics of SOMA ( carisoprodol ) in patients with hepatic impairment have not been evaluated . Since SOMA ( carisoprodol ) is metabolized in the liver , caution should be exercised if SOMA ( carisoprodol ) is dispense to patient role with impaired hepatic occasion .
Indication For Use of Carisoprodol (Soma)
Side Effects of Carisoprodol (Soma)
Less Severe Side Effects of Carisoprodol (Soma):
Severe Side Effects of Carisoprodol (Soma):
Carisoprodol (Soma) Precautions
Drug Interaction- nullify use of Carisoprodol ( Soma ) if following drug or medications to be used simultaneously .
Systemic Disease- Prescription of material body with following condition can be harmful . surplus precaution and strict supervision of treat physician is advised .
Avoid- Carisoprodol is minor downer and may cause drowsiness in normal dosage . Avoid take carisoprodol in the undermentioned circumstances :
Drug Abuse And Dependence
Carisoprodol (Soma) Withdrawal and Abuse
Pediatric Use of Carisoprodol (Soma)
The efficaciousness , refuge , and pharmacokinetics of material body ( carisoprodol ) in paediatric patients less than 16 years of age are not known .
Geriatric Use of Carisoprodol (Soma)
The efficacy , safety , and pharmacokinetics of SOMA ( carisoprodol ) in patients over 65 years quondam is not cognise .
Carisoprodol (Soma) Medications Warning
In Case of Side Effects of Carisoprodol:
Report side effects to Food and Drug Administration ’s ( FDA ) tangency info : www.fda.gov/safety/MedWatcher or call 1 - 800 - 332 - 1088 ( USA ) , 1 - 866 - 234 - 2345 ( Canada ) .
Carisoprodol (Soma) Prescription Instructions
In Case of Carisoprodol (Soma) Overdose:
Sharing Medications
Do not share medications with your ally or relatives . Each individual has different history of allergic reaction , drug interaction , drug shopping , dependency and other general wellness headache . doctor must prescribe medications after point chronicle and examen . Small misplay may be liveliness threatening .
