In October 2007 , the United States US Food and Drug Administration ( FDA ) approved isentress or raltegravir as integrase inhibitors for HIV patients . Its toll run from 17 dollar sign to 4 dollar per oral contraceptive pill .
How Effective is Isentress?
Isentress or raltegravir is a brand of antiretroviral drug that effectively keep the multiplication ofHuman Immunodeficiency Virus ( HIV)in the body . Isentress or raltegravir helps to affix the effectiveness of other antiretroviral drugs . Isentress or raltegravir is an integrase inhibitor due to the ability to in effect restrain the functioning of the “ HIV Integrase”- the sole effort for acute multiplication ofHIV . A patient role can reduce his viral load to the spare minimum if he is close in taking his medications and medical checkup .
Acquired Immune Deficiency Syndrome ( AIDS ) is an advanced degree of HIV . Isentress , which we also known as “ Raltegravir ” is not a cure for HIV and AIDS but acts as an good curtailment or reduction in the viral shipment . Viral load is the amount of computer virus in the roue flow . Someone with the virus can still infect another someone even with the right ingestion of HIV medications .
Cautions Before Taking Isentress
Before the use of isentress or raltegravir , inform your doctor if you have the history of ;
An HIV patient role that has or ever had any of these above diseases should consult his or her doctor before the governing body of isentress or raltegravir . Someone with PKU should also contact his or her physician because raltegravir chewable tablet contains phenylalanine .
The Use of Isentress Among Pregnant Women
There is no validation that isentress or raltegravir will harm a foetus . But , a woman who is significant or plans to be pregnant during the course of the establishment of isentress or raltegravir should first state her doctor .
Pregnant women , who are HIV plus , should be faithful with their medicinal drug to ascertain their viral lode . This is because the computer virus can be send to the fetus if the mother is not careful . Also , breastfeeding mother who are having HIV are not to wet-nurse their babies , because the virus can pass to the tiddler through the chest Milk River .
A significant register is always useable at the clinic for the employment of fraught woman . This is a book where they register their gens to enable a proper follow - up on the state of their maternity . It is also used to supervise the baby after birth and to check up on if the use of isentress or raltegravir by the female parent has any effect on the child . The registry gives the opportunity to give both the mother and child proper medical attention in case of any complicatedness .
What is the Recommended Dosage of Isentress?
The amount of the inhalation of isentress or raltegravir differs in age , body weighting and the level of HIV incumbrance in the body organisation . Isentress also make out in various forms ; film- coated tablet , unwritten suspension , and cuttable lozenge . Oral suspensions are first melt in piddle before exercise .
Isentress or Raltegravir Dosage for Children ( Oral Suspension )
Isentress or Raltegravir Dosage of Chewable Tablets ( Children and Adults )
Isentress or Raltegravir Adult Dosage of Film - Coated Tablets :
It is crucial not to terminate nor reduce the dosage of isentress or raltegravir to prevent the progressive multiplication of the virus . Isentress or raltegravir can be take with or without the intake of food for thought . Peradventure there is unwilled skip of dosage ; there is no need to fear . you may always take it as soon as you remember .
What are the Side Effects of Isentress?
Common side effects of isentress or raltegravir are :
balmy side effects of isentress or raltegravir are hives or reactions of the skin , such as cutis rubor and rash . These skin reactions can strip , spring blister or spread to other parts of the body .
terrible side essence of isentress or raltegravir include trouble in external respiration , body tenderness , high blood force per unit area , fever , dark-skinned coloration of piss , clay color of stools , jaundice , muscle pain sensation , bother in the upper part of the tummy . Other stark side symptoms are fever , pain in the joints , burning mavin in the eyes , swell of tongue , face , sass , and throat .
In rarified case , isentress or raltegravir can cause the breakdown of the tissue paper of the skeletal muscularity . This can further conduce to kidney failure .
If you experience any of these side issue of isentress or raltegravir , it is good to contact your physician or seek immediate health care . you’re able to also discontinue the use of isentress or raltegravir , but on the advice of a medical care giver . Isentress or raltegravir reacts with drugs such as UGT persuader , anticonvulsant , antipsychotic , and antibiotics called Rifadin . Thus , anyone claim these drugs should not take raltegravir without seeing a physician .
Effects of Isentress on Immune System
The use of goods and services of isentress or raltegravir may have counter - effects on the patient ’s immune systems . Isentress or raltegravir changes how body immune systems work . If care is not taken , it can also uproot newfangled infections or certain autoimmune disease .
There are symptoms to look out for to get it on if isentress or raltegravir is working in a reverse agency . The rough-cut ones are highlighted below ;
The Use of Isentress with Alcohol
inebriant breathing in does not make antiretroviral drugs less effective . But it can shrink the layer of bond to prompt intake of dosage . Too much of alcohol can lead to serial publication of hangover . This can make a patient sleep off and skip his or her medicine . Skipping of MEd will be the grounds of the less - effective functioning of isentress or raltegravir .
Another problem is that it can increase dizziness which is also one of the side effect of isentress or raltegravir . Alcohol too can keep down the functioning of the liver . This call for the motive of routine checkup by HIV patients .
Conclusion
Human Immunodeficiency Virus ( HIV ) is not a death condemnation . A patient can live for more than two decades in good wellness with right function of antiretroviral drugs . The intake of isentress or raltegravir should start as shortly as potential , most preferably few hours to the exposure to the computer virus . The optimum continuance of isentress or raltegravir is unknown although the average continuance of its usage is twenty - eight days .
