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Paragangliomas are rarified tumors , with an overall estimated incidence of 1/300,000.(1 )
When the same type of tumour is establish in the adrenal secretor , they are referred to as a pheochromocytoma.(1 )
How Fast Do Paragangliomas Grow?
Paraganglioma is ordinarily a benign tumour that is come up in very a smaller number of guinea pig and it lie in of a special type of neural jail cell which is commonly infer from neural tip cells and is creditworthy for the production of a smorgasbord of hormone . It is a neuroendocrine tumour associated with the production of proteinaceous hormones also known as catecholamines like epinephrine , norepinephrine , adrenaline , and noradrenaline , etc . It is a slowly - growing tumor and usually remains up on the same site because most of them are not known to acquire a metastatic tumour . It does not produce any symptom in most of the cases and remains nameless until it produces some symptoms or become an incidental determination .
Those paragangliomas which get converted to a metastatic tumor are the only ones that grow at a moderate to fast pace . These tumor have to be removed very cursorily because they are known to produce a fate of symptoms .
What Is The Survival Rate Of Paraganglioma?
Since it is a benign and symptomless tumor in most cases , so it does not produce a lot of problem for the patient . These paragangliomas can be separate based on the presence of parasympathetic or likeable neural cells . If the tumor consists of parasympathetic neurons then it is more likely to be present on the base of the skull near the ninth and tenth cranial nerve and is symptomless in almost 95 to 98 % of face . If the tumor consists of harmonic neurons then it is more probable to be present in the belly and pelvis and bring on a lot of symptoms in about 20 % cases .
Since it is a benign tumor , whenever it starts producing symptoms then it should be select very seriously and treated directly . operating theater is the first pedigree of intervention and also the discourse of choice for any paraganglioma because it is almost a hundred per centum curable if diagnose in the earlier state ( benignant state ) and symptoms also subside like a shot . It carries a very unspoiled prognosis because of its non - recurrence nature .
If any of the paragangliomas especially the openhearted one turns into a metastatic tumor and is recover in various places in the body , it becomes very difficult to cure the tumor because it is almost impossible to murder all the neoplasm surgically . The other interesting and demoralizing fact about paraganglioma is , it is a neuroendocrine tumor that does not react well to any case ofchemotherapyor radiotherapy . So , it becomes very hard for an oncologist to treat a metastatic paraganglioma .
Metastatic paragangliomas also convey a high risk of reoccurrence even after successful treatment for the first time because of the presence of some of the malignant cells at unknown locations . But overall paraganglioma is associated with a very adept prospect and a very dispirited return rate.(2 )
Conclusion
It is a benignant tumour and does not rise at a dissipated rate in most vitrine . It can defy all odds to become metastatic cancer and grow at a degenerate pace in a very small number of cases with the epidemiology of less than one such vitrine per million .
Whenever it is associated with a low paced growth then there are very good chance of complete remotion of the tumour surgically . The affected role becomes also asymptomatic within few weeks but in some cases , it can be present at such a web site that it is case a cranial nerve and becomes a very difficult type for removal . Overall , it carries a very good medical prognosis with a high success rate .
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