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Peripheralneuropathyis a common experimental condition observe in the population because of its diversity of causes . This condition having a large number of lawsuit few of which arediabetes mellitus , chronic liver disease , continuing kidney disease , metabolic disorders , Charcot Marie tooth disease , autoimmune disorders , drug - induced , radioactivity , etc.[1 ] .
Is Peripheral Neuropathy A Serious Condition?
In the epidemiologic datum of India , the relative incidence of peripheral neuropathy has been determined between 5 to 2400 among the population of 10,000 in various different studies done on multiple communities[2].A number so high is very much sinister and stupefy a serious problem for the doctors as well as the health system . It becomes problematic for the saving of the country because it leads to a gamey handicap pace and also gives emphasis on the fact that causes are increasing multiple times which is leading to such a turgid number of sheath .
The non - therapeutic nature of the neurones after the harm incurred to them makes it even more serious to get by with because they can not be replaced . It makes the disability lasting and also proves to be debilitating for the affected role ’s quality of life . With the loss of trophic factors released by the nerves , it becomes hard for the muscles to conform and they undergo atrophy and wasting . Trophic nonhealing ulcers develop shortly after the loss of cutaneous nervus sensations and can even advance to a degree where the amputation of the limb is necessitate to save the patient[3 ] .
Can Peripheral Neuropathy Be Reversed?
Peripheral neuropathy is the harm receive to the mettle which can be centripetal or motor in nature . The chemical mechanism of harm in the majority of the case is demyelination of the boldness and personnel casualty of Schwann cell covering the myeline case . Sometimes axonal legal injury via Wallerian decadence can also occur as the chemical mechanism for neuropathy .
The reverse of the peripheral neuropathy depend upon the cause and extent of the condition . Few causes are known which only temporarily make malfunctioning of peripheral nerves acquaint as peripheral neuropathy and can be cured once the aggravating and precipitating factor is dispatch . In initial stages when the earliest symptom have just started to appear there may be a black eye of neuropathy because only a few cell are damage and can be compensated by other nerve cells .
Absolute change of mind of peripheral neuropathy is usually not seen because the neurones are the non - proliferating character of jail cell and the damage cells can not be replaced by Modern I . Once the symptoms have increase towards severeness , it is impossible to reverse the condition . No medical discourse or drug has been divulge which could effectively bring around the neural harm and induct its reversal . Only supportive treatment can be given to reduce the symptoms and improve the timbre of life .
With the Second Coming of unexampled technical advances in the medical field , it has been now potential to set the damage by the cheek graft proficiency to replace the damaged mettle . A transdermic electric nerve stimulation organization can be established at the peripheral web site of nerve equipment casualty which can supply uninterrupted impulses when expect to correct for the loss of nervus stimulation.(1 ) ( 3 )
Conclusion
Peripheral neuropathy ’s widespread causes and its irreversible nature makes it a serious condition that should not be taken lightly and immediate intervention should be get hold of for bound the disease . It is also responsible for causing severe handicap like amputation of the limb , bony deformities , development of contracture , muscular wasting , etc . which increase the oeuvre hours lost to the disability and bear on the productiveness of patients . The patient can become dependent and the quality of life is affected severely .
Reversal of the already go on hurt can not be done but its limitation to the extent can be done with rigorous control of the causative broker and use of supportive intervention for it . Although various research labor are being quest after no discussion has been found supporting the reversal of peripheral neuropathy . The prevention remain the key for its minimisation .
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