Rett syndrome is a upset of the brain , which occurs exclusively in fille . This clause deals with the common concerns of whether Rett syndrome is contagious and if a somebody with Rett syndrome can have child .
After birth , the girlfriend who have Rett syndrome have 6 - 18 months of normal growth prior to the growing of severe problems with learning , communication and terminology , coordination and brain functions . In early puerility , the dissemble little girl lose the skills of how to habituate their hands and lock in repeated script washing , wringing , or hand clapping motions . They grow slow compare to other children , and most of them have small head size . Other symptom and signs that develop admit spitting or drooling , external respiration abnormalities , strange eye drift like excessive blinking , irritability , cold foot and hand , seizures , sleep disturbances , and unnatural spine curve . There are four phase in a Rett Syndrome .
Is Rett Syndrome Hereditary?
come to the question , is Rett Syndrome patrimonial ? The fact is that Rett Syndrome is a genetic disorder but the way in which the genetic changes occur and the manner they affect varies . Classic Rett Syndrome and several discrepancy of this syndrome with soft or life-threatening symptoms may happen due to specific genetic mutation . The genetic sport which causes this disease happens randomly , generally in the MECP2 cistron . Only in some cases , this disorder of genes is inherit . The mutation results in problems with critical protein production for development of the brainiac . The exact cause is still unknown and it is being studied .
As the chromosome combination in males is dissimilar from female , a virile baby with a genic chromosomal mutation , which causes Rett syndrome , does not become affected in such a withering way as compared to a distaff child . A few number of boys have a different mutation that cook Rett Syndrome less destructive .
Rett syndrome is a hereditary disorderliness ; it means that it is triggered by the faulty factor . Less than 5 % of the recorded cases are passed or inherited from one generation to another . Generally , mutation happen during the division / replication of chromosomes and more commonly during organization of the spermatozoan and less commonly during the formation of the ballock . Thus , many Rett syndrome happen at random instead of being inherit . Still , there are many cases where the parent carry it and clusters of these cases within the families are found in the special geographic region like Norway , Sweden , and North Italy .
These 24-hour interval , it is recommend that mothers of children have Rett syndrome should have their carrier testing done . forefather are less likely to be postman because of the very fewer case of Rett syndrome in male . If the mother is persuade the syndrome then the risk of occurrence in the next tiddler is 50 percent . If she is not a carrier then the risk of happening is below 0.1 percent . Since Rett syndrome come due to mutation in factor , recurrence risk variegate from child to child .
Can a Person with Rett Syndrome have Children?
Another common headache that bothers families with such casing , is that can a person with Rett Syndrome have kid ? There is no cause as to why a person with Rett syndrome can not have children . In charwoman , there is an inactivation between X - chromosome that contain the mutant . It means that the circumstance may be from a liveliness - threatening and challenging phenotype that can be hardly noticed or be undetected for many years .
There have been cases of mother hump to be mutation carriers and have children suffering from Rett syndrome ; however , it is arguable whether they are Rett Syndrome sufferer themselves till the time they are diagnosed for Rett syndrome .
Male carriers of Rett syndrome mutation usually do not survive till adulthood because they do not have the advantage of the 2d X - chromosome . However , if a male child having Rett syndrome also suffers from Klinefelter Syndrome , wherein they have a 2nd X - chromosome apart from Y - chromosome , they can survive .
Conclusion
Rett Syndrome is a genetic condition that occurs due to sure genetical change and may affect the adopt propagation in varying way . However , it is very much possible for a soul with Rett Syndrome to have children . Genetic cover is extremely commend for home having this condition to asses the risk and take necessary activity , as appropriate .
multitude with Rett Syndrome symptom continue to go the right way till middle historic period and after that too . As the upset is very rare , there is short knowledge about life expectancy and long - terminus prognosis . There are many women in 40 and 50 who are hold up with this disorder ; currently it may not be possible to make an estimation about life story expectancy after the age of 40 . Researchers are finding out other genes that can be ask in Rett syndrome . Some studies have narrowed down these genes , but it is still not known whether the genes can contribute to or cause Rett syndrome .
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