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The neurilemoma is a neoplasm located in the peripheral heart . It leave from the anarchic propagation of different cells take shape the perineurium , supporting connective tissue surrounding these peripheral nerves . It is to be differentiated from the neuroma that develops from Schwann cells . The appearance of neurilemoma is chiefly due to hereditary genetic diseases , called von Recklinghausen’s disease .
The most distinctive instance is neurofibromatosis or Von Recklinghausen ’s disease nock by the development of small tumors at unlike sites . The consequences of the mien of neurilemoma can be more or less serious depending on their size and their locating in the body.1
What Are The First Symptoms Of Neurofibromas?
neurilemoma 1 usually has no symptoms , except for characteristic coffee - milk - colored spots or nodules ( neurofibromas ) under the hide . moved people may not notice spot or tubercle . However , when neurofibromas compress nearby nerves , hoi polloi may have tingling or weakness in areas near the tubercle .
burnt umber - milk - color spots develop in about 90 % of involve kid . They acquire on the peel of the thorax , back , pelvis and in the hollow of the cubitus and knees . These spots may be present at birth or seem during babyhood . Children without neurofibromatosis may have two or three coffee berry - latte spots , but children with type 1 neurilemoma have at least six such spots .
Other symptom of neurofibromas1include :
In neurofibromas2 , acoustical neuroma break on one or both auditory cheek . Tumors can cause hearing loss , ringingwheezing(tinnitus ) , instability , giddiness , and sometimes headache or failing of certain parts of the fount . Symptoms can look in childhood or former adulthood .
People may also have other type of neoplasm , including glioma and meningioma ( tumors that appear in the head or near the brain ) , and some develop earlycataracts2 , 3 .
Schwannomatosis
In schwannomatosis , benign tumour ( schwannomas ) can appear on almost all the nerves in the body , with the exception of the audile nerve . Some the great unwashed have many schwannomas , but others have only a few .
The first symptom of schwannomatosis is usually a pain in the neck that can become chronic and severe . Some hoi polloi go through spiritlessness , tingling , or weakness of the fingers and toes . Other symptoms may occur , depending on the fix of the schwannoma(s)4 .
How Do You Test For Neurofibromas?
aesculapian history of the patient and physical examination are unremarkably enough to diagnose neurofibromas . If further analysis is demand , your doctor may choose for imaging scans such as CT , MRI , and PET .
Types Of Neurofibromatosis
There are three character of von Recklinghausen’s disease ( eccentric 1 , Type 2 , and Schwannomatosis ):
case 1 ( NF1 ) involve about 1 individual from 2500 to 3000 . The neurofibromas develop along peripheral nerves , for exemplar on or in the skin and just outside the spinal cord . Sometimes neoplasm develop in the nerves that connect the brain to the eyes ( optical spunk ) . Bones and soft tissues ( such as muscles ) can also be bear on .
Type 2 ( NF2 ) is less plebeian and affects about 1 mortal in 35000 . It causes tumors of the auditory nerves ( which connect the privileged auricle and the brain ) , called acoustical neuromas , and sometimes tumors may develop in the brain or the tissue surrounding the brain or spinal cord ( meninx ) . Tumors located in the meninges are called meningioma . These tumors are benignant in nature ( not cancerous)2 , 3 .
The Schwannomatosis4 is very rare equate to the other two types . In this case , neurofibromas develop around peripheral boldness but do not move the auditory nerve .
Conclusion
Neurofibromas are a small benign neoplasm that bear upon the nervous organization . It occurs due to a genetic upset . People with this disease have non - cancerous tumour along the nerve footpath . Symptoms of the disease vary from discoloration of the cutis ( coffee - Milk River - colored spot ) , hearing difficulty or bone deformities . They mostly look at the time of birth or during infancy . This status can affect man as well as woman of all ethnic groups .
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