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Kawasaki disease cause rubor in the arteries wall in the body and the firing further affects coronary artery i.e. arteries responsible to furnish bloodline towards the heart muscles of patients .
What Are The Stages Of Kawasaki Disease?
If we talk about the clinical course of kawasaki disease , it lie of four unlike phases or stages . These let in the following-
Acute Phase / Stage of Kawasaki Disease- Acute phase / degree , which lasts for about 1week or 2weeks in child and in fount , if you leave it untreated , your child experience a vast spike in the body temperature or fever at about 40 level Celsius . In improver , he / she get various principal symptomatic feature of speech and presents cardiac manifestations in the form of myocarditis , pericarditis and valvitis .
Sub - Acute Phase / Stage of Kawasaki Disease- Sub - acute phase of the disease survive for or so 2weeks followed by abatement of your kid ’s febrility , when he or she remain at a high hazard concern to sudden demise because of myocardial infarction .
Convalescent Phase / Stage of Kawasaki Disease- physician call this as the clinically unseeable phase angle / stage , convalescent form / degree of Kawasaki disease follows the cessation of various Kawasaki disease symptoms and it continues until the reactants of your kid ’s acute phase coming back to the even serum levels .
Chronic Phase / Stage of Kawasaki Disease- Chronic phase or stage associated with Kawasaki Disease highlights those patients , who want follow - up and management because of their engagement of coronary arteries.(1 )
Kawasaki Disease Management as Per Phases/Stages and Respective Complications
Kawasaki Disease Management at its Acute and Sub-Acute Phases
The main objective behind piercing and sub - acute phase in Kawasaki Disease is to reduce the problem of firing , specially coronary arteritis and myocarditis . For this , doc have validated IVIG id est Intravenous Immunoglobulin as the first - production line treatment to heal keen phase of Kawasaki Disease in most of the prospective levels of multicentre treatment trails .
concord to the American Heart Association , patients should undergo handling by only one IVIG infusion for more than 12hours and the dose in this case should be 2gram / kilogram in 10days of the onset of febricity . In addition , doctors advocate for anti - incitive 100miligram / kg of Empirin dose to scatter out more than 4 United States Department of State until and unless the affected role becomes afebrile .
Kawasaki Disease Management At Its Chronic Phase
The main object behind continuing stage management of Kawasaki Disease is to nullify the occlusion of coronary artery and myocardial infarct via reducing the aggregation of platelets and inhibition of thrombogenesis . Long - full term treatment options in this case call for anti - platelet acetylsalicylic acid dosage of about 3miligram to 5miligram per kg in a day until and unless you come after to see normal echocardiograph within only 6weeks to 8weeks .
patient associate with coronary arteria involvement often demand antiplatelet St. Joseph DoS on a tenacious - term basis . Besides this , patients suffering from multiple or giant aneurism command systemic anticoagulation therapy by using low molecular weight unit of heparin . Heparin treatment is perfect to prevent hard bleeding and hence , it constitutes a viable selection among many young patient dealing with coronary arteria involvement in its severe form .
Symptoms of Kawasaki Disease
Kawasaki disease symptom take place in three different phases-
1st Phase i.e. Acute Phase-
2nd Phase i.e. Sub-Acute Phase
3rd Phase i.e. Chronic Phase
References-
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