Lichen Planus pass as a upshot of various element in the human trunk that spark the immune system . These factors can order from other disease , drug medications to environmental agent . In this font , we are go bad to concentrate on Lichen Planus set off by drug medication referred to as drug - induced lichen planus or lichenoid drug eruptions . In fussy , we ’ll live on rake insistency medications that might touch off lichen planus . Drug - induced LP can involve various parts of the consistence including the mouth , tegument , arms , and legs too . In general , lichen planus affects about 1 % of the adult population – 45 - yr - old and above . still , even children can be regard .
What Blood Pressure Medications Cause Lichen Planus?
It is important to note that not all drug used for blood pressure will stimulate lichen planus . The main ones that have been linked to this autoimmune stipulation let in ; antihypertensive drugs , genus Beta blocking agent , and angiotensin - converting enzyme ( ACE ) inhibitors . The governing of these drugs have this circumstance as a side result and more than often it earn away when the affected role halt study the drug . Having a risk of infection factor of developing lichen planus does not of necessity think of you ’ll get it . Also , lack of the risk of infection cistron does n’t imply you will not contract either . Since line pressure medicine is administered orally , they often cause unwritten lichenoid bam .
Lichen Planus and Antihypertensive Drugs
Antihypertensive drug are used in treating hypertension with the aim of preventing high blood pressure sensation ramification . They are often used in combating strokes andheart onrush . Antihypertensive drugs have extremely been assort with oral lichenoid volcanic eruption . Oral Lichen Planus occurs in the mouth and appears as white lace - corresponding patterns on the tongue or gum . With time , they may ulcerate and cause corroding where they bet like red lesions with blanched borders . ACE inhibitors and Beta Blockers are a part of the antihypertensive drug classes . However , not all classes of drug under antihypertensive drug cause drug - induced lichen planus .
Lichen Planus and ACE Inhibitors
Angiotensin - converting enzymes ( ACE ) inhibitors are used in the discussion of various illness including migraines and mellow blood line press . They are efficacious in that they loosen up blood vessels by preventing an enzyme in the body from releasing angiotensin II . Angiotensin is an element that constrict blood vessels and releases hormones , which can raise your blood insistency . ACE inhibitors have been linked to mucosal lichen planus , which affects the sassing and genitals , specially in fair sex . Studies have been done to establish the link and the issue show an inverse relationship between ACE inhibitors and mucosal lichen planus . However , further studies will be relevant in confirming or deny this relation .
Lichen Planus and Beta Blockers
Beta Blockers also get laid as beta - sympathomimetic blocking agents or β – blocking agent are used in the treatment of various heart problem . They are used for high blood press , continuing spunk failure , irregular heart rhythm , ischemic heart diseases and atrial fibrillation . Beta Blockers go by blocking the effects of epinephrine endocrine , i.e. adrenaline . They also help in opening up rip vas to enhance blood flow . Lichen planus drug volcanic eruption have been connect to the use of beta blocker that hold in the mouth and various part on the peel . So , this is an evident sign that lichen planus is a side force of use of beta blockers . On the skin , drug - cause lichen planus manifest as small red / purple gibbousness with ashen bit and streaks . They can ignite into blister but are often painless .
Conclusion
As much as lichen planus can be due to aspiration of different blood pressure medications , you should only stop taking them after check with your MD . Drug prescriptions are made with an intention to treat a sure illness and miss the dosage can bear witness to be more disastrous . blizzard due to lichenoid drug volcanic eruption should clear up when you barricade taking the drugs . This acts as a verification or rather diagnosis for the front of lichen planus and your allergic reaction to the drug . In case where the medicine can not be ceased , other alternatives are see to relieve the symptom .
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