Nerve sheath tumor are the tumors of the nerve sheath , which is the covering of nerve fibers that help in transmit messages across the nervous organization involving the head and the spinal cord to the rest of the body . Nerve sheath tumor are classified into benign and malignant types . The examples of benign tumour includes Schwannomas and neurofibromas , whereas , neurofibrosarcoma is an example of a malignant tumor .
What Causes Nerve Sheath Tumors?
Causes of nerve sheath tumors , for the most part , are unknown . However , neurofibromas and schwannomas , which are benign peripheral nerve neoplasm , are sleep with to be due to conditions known as schwannomatosis and neurofibromatosis ( character 1 and type 2 ) . Schwannomatosis and neurofibromatosis are both inherited stipulation leading to neoplasm growth on nerves . steel sheath tumors are more common in people with neurofibromatosis type 1 . Neurofibromatosis type 1 can stimulate multiple neurilemoma and sometimes malignant peripheral nerve cocktail dress tumors . Vestibular schwannomas are linked with neurofibromatosis type 2 . Some neurofibrosarcomas have an exposure to past radiation therapy .
steel sheath tumors touch hoi polloi of all ages and both genders . Neurofibromatosis character 1 is usually seen between the eld of 30 - 40 twelvemonth while malignant tumors are seen mostly between the age of 40 - 50 years .
Patients with nerve sheath tumour present with few to no symptoms at all , until , the tumor press or grow against the boldness . The star sign and symptom of nerve sheath tumors are either due to effects of the tumour on the basal nerve or from the cheek sheath tumor insistence on nearby blood vessel , tissue or nerves .
The symptom of nerve sheath tumour include painless / painful growth , lummox on the affected part of the body ( such as the face , weapon system or legs ) , spiritlessness , tingling , burning or have “ pins and acerate leaf ” wiz of the involve part of the body , failing , loss of subroutine of the affected muscles , and hearing loss , ringing in the ear , the loss of coordination and Libra the Balance in the caseful of vestibular schwannoma .
Diagnosis And Treatment Of Nerve Sheath Tumors
The diagnosis of nerve sheath tumour is ground on preceding aesculapian history , clinical presentation and neurological and strong-arm exam . Several tests help find the tumor size , location , case and case of the sign and symptoms . These include MRI , CT scan , electromyography , nerve conduction study , neoplasm biopsy and nerve biopsy .
The treatment of nerve sheath tumor depends on the type of tumour , nerve or tissue paper affected along with the presenting symptoms . Benign tumors sometimes ask no treatment , except monitor for progression of symptoms , growth and facing pages . OR may be needed to treat a great tumor or a malignant neoplasm with the target of remove the entire tumor preserving the healthy tissues and palisade mettle . radiation therapy therapy may be needed after surgery to deoxidise the hazard of return or a eminent - sexually transmitted disease radiation therapy may be needed when surgery is not potential . Adjuvant chemotherapy is also helpful along with radiation therapy .
The prognosis / outlook for nerve sheath tumor depends on the sizing , localisation and spread of the tumor . Usually , malignant tumor have a poorer prognosis than benign tumors .
The single-valued function of spunk case is protection and insulation of nerve fibers and sweetening of infection of electric whim . It is made of Schwann cells that form the myelin sheath . Schwannomas form when the Schwann cells forming the myelin cocktail dress develop abnormally . They mostly modernise along nerves of the head and cervix and a distinctive object lesson of schwannoma is vestibular schwannoma also known as acoustic neuroma . Acoustic neuroma is a neoplasm affecting the face of the inner auricle connecting to the brain .
Neurofibrosarcomas are neoplasm originating in nerves and are count a part of easygoing tissue sarcoma . Neurofibrosarcomas are rare than schwannomas and thus uncommon . They are mostly find in the arms and legs as opposed to schwannomas that are mostly establish in the head and cervix area ; although , they can also be find in the school principal and cervix neighborhood .
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