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Blood watercraft are present in every part of the soundbox and if there is any disorder in the rakehell vas , the disease may have a multiorgan impact . Such is the showcase with Kawasaki disease . If left untreated , it may head to complications in various reed organ .
What Happens If Kawasaki Disease Goes Untreated?
Cardiovascular Complications : Cardiovascularcomplications are the common conditions in patients with Kawasaki disease . It importantly feign the morbidness and deathrate of these patients . The various cardiovascular complications involve coronary artery ( CA)aneurysms , peripheral arterial occlusion , heart loser , and myocardial infarction , reduced myocardial contractility , andcardiac arrhythmia . The risk of infection of cardiovascular complication is eminent in untreated patient as compared to deal patients . ( 1 )
Kawasaki Disease Shock Syndrome : The patient suffering from Kawasaki disease may build up a life - threaten precondition known as shock syndrome . The precondition is characterized by low blood perfusion and the ancestry pressure trim sharply in such case . It should be note that the intervention of such jar due to Kawasaki disease is the brass of intravenous immunoglobulin which is not appropriate for the intervention of other shocks . The symptom of Kawasaki disease stupor syndrome areanemiaand thrombocytosis .
Macrophage Activation Syndrome : The condition is also known as secondary hemophagocytic lymphohistiocytosis . It is a lifetime - threatening complication of Kawasaki disease . It is generally the underrecognized complication as the pathophysiology and cause of the disease is not clear . The symptoms that may indicate the presence of macrophage activation syndrome in Kawasaki disease are hyperferritinemia , hypertriglyceridemia , elevated serum LDH , cytopenia , hypofibrinogenemia , and hepatic disfunction . Splenomegaly may also indicate the presence of macrophagic activation syndrome .
Urinary Tract Complications : The complications of Kawasaki disease may also involve the kidney and urinary pamphlet . These ramification may be due to the fervour of the renal parenchyma because of tetraiodothyronine - cell activating . Vasculitis may also cause vascular endothelial injury in the nephritic artery . The symptom of kidney and urinary tract complication include haemolytic azotemic syndrome , tubulointerstitial nephritis , prerenal acute kidney injury , and pyuria .
Gastrointestinal Complications : GIT involvement is a vulgar natural event in the affected role with Kawasaki disease and the charge per unit of amour is around 2.3 % . The ecumenical symptoms are hepatomegaly , paralytic intestinal obstruction , diarrheawithabdominal pain , emesis , and abdominal distension . However , the complications of the GIT are quite rarefied and let in appendicular vasculitis and hemorrhagic duodenitis . The precondition may be caused due to spartan excitement in the brawny layer and other stratum of the bowel and shows the signs of necrosis and degeneration .
Nervous System Complications : Kawasaki disease also affects the queasy system . Various symptom related to the complication of the spooky system includemyositis , epilepsy , andhemiplegia . Facial nerve paralysis has also been seen in various patients . Analysis of cerebrospinal fluid also indicates the comportment of pleocytosis .
Treatment Of Complications
Medications : Various medications such as antiplatelet and anticoagulant , the medicines which forbid the clot formation , are used .
operation : Various surgeries can be advised by the cardiologist on the basis of disorder come about due to complications . When the coronary artery gets blocked , the treatment advised may be coronary angioplasty through which the blocked artery be opened . But if the coronary angioplasty is not possible , then coronary arteria electrical shunt grafting may be advised .
Conclusion
asunder from the cardiac knottiness , the Kawasaki disease may lead to gastrointestinal , anxious organization and kidney complication .
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