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What is Chemical Castration?
Using anaphrodisiac drugs to lower sexual desire orlibidois known as chemic expurgation . The treatment lowers the levels of manly hormones or androgens .
Androgens i.e.testosteroneand dihydrotestosterone are mostly made in the testicles and residual come from the adrenal glands(1 )
Luteinizing hormone - releasing hormone ( LHRH ) comes from the pituitary glands signals the testicles to make testosterone . The LHRH protagonist stimulates the product of luteinizing endocrine . This causes the testosterone levels to rise .
The effect hold out for a few weeks . take anti - androgen for a few calendar week can alleviate the concern .
If the LH levels are raised , their production from the pituitary gland stop . It no longer signal the testicles to make androgens . This reduces the testosterone levels to very low , just like operative expurgation .
What are LHRH Agonists?
LHRH agonists are also have intercourse as gonadotropin - releasing internal secretion ( GnRH ) protagonist . They do not affect the production of androgen in the adrenal secretory organ instantly , as anti - androgens do .
Some of the LHRH agonist are :
Chemical Castration Procedure
Chemical castration is a one - clip treatment in which the doctor inject the drug or implants them under the skin .
count on the drug and the Venus’s curse , it would be repeated once a calendar month or once a year .
In the showcase of advanced prostate gland cancer , LHRH antagonists are recommended by the Dr. as they work quicker than LHRH agonists . They do not do an increase in testosterone levels . LHRH adversary include the following medicines :
As long as a mortal is under drugs the event of chemical expurgation stays . The hormone production getting even to normal once the drug are end . The effects are also two-sided , but in some case where the medicines are continue for long , the side effect may remain .
Side Effects of Chemical Castration
There are a few side gist related to chemical castration , which include :
Long term side effects admit :
The longer you are under handling , side effects and complications increase(2 ) . Therapies are commend by the Doctor of the Church to keep or ease the side effect .
There are also a few concerns that the men treated with chemical emasculation are at the risk of :
Difference Between Chemical Castration and Surgical Castration
Chemical castration is done using unwritten medicament , injections , or implants to lower the internal secretion level . There is no immediate change in the show of the testicles .
They might funk over time and in some cases , they become so small that you could not even feel them . The effect of chemical castration lasts as long as someone is under the intervention . As the handling kibosh the modification is two-sided .
Surgical expurgation , also known as orchidectomy , imply the removal of both the testicles . This procedure reduces the levels of testosterone in the blood(3 ) .
It is an outpatient process and once done can not be reversed .
A subprogram that involves the remotion of the tissue paper that produces androgen instead of the entire testicle is call subcapsular orchiectomy . This continue the scrotum integral . In some case , unreal bollock are inserted into the scrotum .
Uses of Chemical Castration
chemic castration is used in the treatment of endocrine - dependant cancers such as prostate gland cancer . It slows down the Crab growth and metastasis .
The discourse can be beneficial in the prostate cancers that have spread or recur after first - stock treatment .
Chemical emasculation can also be used to slow the progression of malebreast Crab .
The patient role require to inform the doctor of any music they are pick out , including the over - the - counter herbal medicines , while undergoing the treatment . Some herbal medicine interact with a drug - metabolise enzyme in the trunk and can lead to inauspicious effects(4 ) .
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