What Is Plaque Morphea?
Plaque morphea is a superficial character of lesion get in the derma of the skin . The control surface becomes smooth , bright and hairless with going of sweat secretor and over time the affected arena may become sunken and depressed . It can further be divided into several types include , plaque morphea itself that consist of sclerosis of cherry , swollen , ellipse to assail , bloodless - yellow gloss along with central depression , in addition to Bolshevik to purple edges ( lilac ring ) . The second form is the ring morphea , in which rotary eccentric of induration is seen affecting the extremity . The third grade is the guttate morphea , which consists of several small grouped lesions of several millimeters that are snowy , shining , depressed without any sclerosed changes and are mostly regain in the chest orbit . The fourth type is keloid morphea , which is characterise by typical memorial tablet with freestanding nodules or united nodules have appearance of a keloid scar . The 5th type is lichen sclerosus et atrophicus that consists of white atrophic macule and small plaques . The sixth smorgasbord is atrophoderma of Pasini and Pierini , which has a questionable category and presents as hyperpigmented and asymptomatic patches with “ cliff drop borders ” happen mostly on the trunk and extremities .
Other than brass morphea , the wide accepted categorisation in medical sodality classifies morphea ( localise scleroderma ) into four subgroup . These include-
Bullous Morphea : Bullous morphea comprise of surd subepidermal bullae along with typical morphea or deep morphea .
Generalized Morphea : Generalized morphea is a more severe signifier of morphea that extends in a wide expanse of the skin and can also necessitate the underlying muscles .
Linear Morphea : Linear morphea as the name implies is characterized by one or more additive lines that may involve the dermis , hypodermic tissues , muscle and os . It can be find on the appendage , scalp , or face of tike or adults . En coup de sabre is a rich conformation of linear morphea that affects scalp and tabernacle region of a person . This may involve the underlying skull bone that may cause shrinkage and deprivation of hair’s-breadth in the country . When linear morphea crosses a reefer , may affect the mobility or functioning of the limb .
Deep Or Pansclerotic Morphea : mysterious or pansclerotic morphea involve the underlying subcutaneous tissue , sinew and bones . It is mostly found in child and can be disabling when a os is involved . It can lead to scrubby growth of the involved bone .
The treatment of morphea should be based on the type of morphea as most of them are benign case and regress spontaneously within 3 - 5 age with a favorable final result . Plaque morphea is a ego - limit form with better esthetics , so should be treat with topical adrenal cortical steroid , calcipotriol ( vitamin D substitute ) , tacrolimus 0.1 % , imiquimod 5 % or Hyazyme to reduce inflammation and preclude advance of the lesion . Phototherapy has also proven successful for the treatment of morphea .
Scleroderma
Scleroderma is a chronic autoimmune disease point connective tissue and blood circulation leading to fibrosis and surround blood line vessel obliteration . Scleroderma is categorized depending on the extent of cutis and harmonium engagement and is principally of two types , namely , localized genus Scleroderma ( morphea ) and systemic scleroderma .
Systemic scleroderma is a more life - endanger variation of scleroderma in which along with diffuse sclerosis of peel and underlying connective tissue , calcinosis , Raynaud ’s phenomenon , esophageal disfunction , sclerodactyly , telangiectasia , inner reed organ ( lungs , kidneys , GI tract ) are also sham .
Localized scleroderma or morphea is a benignant and more common shape of scleroderma that only affects skin , subcutaneous or underlying musculus of trunk and member . Morphea is unremarkably chronic , ego - limiting with a friendly prognosis . Both localized and systemic scleroderma are more commonly seen in fair sex than in men . The prison term of occurrence is mostly during puerility , adolescent or young grownup phase angle , but multitude of any age may be affected .
redundant collagen deposit by fibroblasts is the main culprit behind morphea ; however , the precise cause behind this deviate behavior of fibroblasts is still undecipherable .
Autoimmunity , genetics , infection , injury or toxicity have been suggested etiology and trigger factor .
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