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MRSA is acronym for- Methicillin Resistant Staphylococcus Aureus . The scientist had discovered staphylococcus aureus in the eighties and in the period of late forties this bacterium began to metamorphose and was found to be resistant to penicillin . And so the doctor startle using the antibiotic methicillin for address the infection . afterward in the class of 1961 , it was chance upon that now these bacteria have gained resistance to amoxicillin as well as methicillin . Methicillin is a kind of antibiotic that belong to the penicillin group . in the first place this antibiotic and other antibiotic drug from the penicillin group were wide used for the treatment of Staphylococcus Aureus contagion and because of its over usage now Staph . Aureus has gained resistance against these antibiotic drug as well as against methicillin . And hence these bacteria have been given the name MRSA .
What Is The Strongest Antibiotic For MRSA?
MRSA can be treated either by oral or intravenous antibiotics . Some of the intravenous antibiotics used are :
Vancomycin : It interferes with the bacterial cubicle wall product by blocking the formation of peptidoglycan leading to bacterial death . This is the most widely used antibiotic that is very in effect in treating MRSA . It is used as a first line of products drug . Dosage- 30mg / kg , the STD must not be give way more than 2 g within 24hrs time period . Administration is done slowly over a period of 90 second otherwise it may lead to “ red man syndrome ” . Red man syndrome- it is a sort of hypersensitivity response that require emergency medical management.(1 )
Daptomycin : This antibiotic is used as a 2nd line of treatment . Dosage- 4 to 6 mg / kg
Linezolid : This is used as a third line of discussion . Dosage – 600mg/12 hourly . Side effects- lactic acidosis , thrombocytopenia , etc .
Tigecycline : This is used as a fourth air of discussion .
Dalfopristin : This is used as a fifth phone line of management .
antibiotic that are give orally to treat MRSA :
Trimethoprim And Sulfamethoxazole Combination : It is used as a first line of treatment . It is also an in force unwritten drug .
Clindamycin : This is used as 2nd line of treatment . Bacteria may gain immunity against it .
Doxycycline : It is used as third air of management .
Linezolid : It is used as a 4th line of direction .
Rifampin : It is not used alone but in combination with other drugs.(1 )
Medicines that are ineffective in the treatment of MRSA :
Treatment Of Local Skin Infection
Incision And Drainage Of The Skin wound : The skin wound may incorporate pus within , this must be incise and the pus should be drained out .
Culture And Sensitivity : The collected pus sample distribution must be sent to lab for culture and sensitivity testing . Antibiotic treatment must be cave in consequently .
Symptoms And Signs Of MRSA
Symptoms of deep tissue paper contagion and blood intrusion :
These were the sign and symptoms of MRSA . The presence of these signs and symptoms does n’t necessarily reason out the presence of infection . Other laboratory tests are also done to confirm the diagnosis . Culture and sensitiveness test are done . Nasal swab and pus from skin lesion is compile for the tryout .
After confirmation of the disease , right treatment must be started now . Suitable prophylactic actions must be taken to control the counterpane of infection to the hefty people coming in contact with the patient . Proper hygienics must be maintained . All this will lead to good convalescence of the patient and also avoidance of transmission to other people .
Conclusion
There are many drug available for the handling of MRSA but the most ordinarily used and the strongest antibiotic is “ Vancomycin ” . It is a very effective drug and the response to the treatment with it is quick and noticeable .
It effect the peptidoglycan yield that is very essential subject matter necessary for the mobile phone wall production of the bacterium . This leads to death of bacteria due to damage cadre wall . Along with vancomycin other supportive therapy may also be given .
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