Long QT Syndrome ( LQTS ) is a condition in which the heart go wrong to provide the ancestry efficiently to various division of the body . This is due to the abnormal ion regulating within the heart essential for optimizing the conductivity of electric impulses . This result in the fast and non - rhythmical heartbeat and if such a situation continues for a long time , it may ensue in cardiac arrest or sudden death . The syndrome may be either acquired or congenital and it may occur due to the use of goods and services of certain medication , which interfere with the regulation of ion in the kernel . There are sure as shooting other causes such as low concentration of calcium or potassium in the blood , which is also essential for maintaining the cardiac regular recurrence .
What Medications Can Cause Long QT Syndrome?
Long QT syndrome is divide in to two types on the basis of happening of this condition . In congenital LQTS , the syndrome is present at the fourth dimension of nascency as the gene which are responsible for maintaining the ion proportion in the pump becomes abnormal . In acquired long QT syndrome , the affected role suffers from this syndrome by and by in his life . The causa of acquired LQTS is low atomic number 20 and abject atomic number 19 in the blood and also attributed to various medication which interfere with the ion exchange within the center .
In the acquired farseeing QT syndrome , the reason is due to the blockage of hERG channel , which can be due to certain medications . These medications , due to their side effects are either withdrawn from the marketplace or contraindicate in the multitude with such condition .
Symptoms
warmness has the function to maintain the ancestry flow to various organ . In farsighted QT syndrome , this mental ability of the essence is greatly reduced , and the results start appearing in the form of symptoms . When the roue provision is reduced , there is an overall fatigue duty in the soundbox . Further , the organ mostly affected are mental capacity . When the blood supply is lowered in mentality , the patient starts feel conk , a condition sleep with as syncope . Further , there are seizures like effect in the brain . The precondition is diagnosed when the affected role experiences cardiac symptoms . Further , in some cases , the condition remain undiagnosed as there are no symptom and is founded during unremarkable checkup .
Conclusion
inborn long QT syndrome is due to the variation in factor keep in line the catamenia of ions in the affection . However , acquired LQTS is generally due to the obstruction of the flow of ions . Certain drug are involved in such obstruction . These drugs are either removed from the market or , if they are present , are contraindicate in the patients with long QT syndrome . These drug are from various therapeutic categories and include the major tranquilliser , antidepressant , GI drug , antimicrobic , antimalarials , antiprotozoal and antiarrhythmic drug . As the LQTS has life - threaten implications thus such drug should be used with utmost precaution in the patients with long QT syndrome .
Also Read :
