This clause on Epainassist.com has been reexamine by a medical professional person , as well as checked for fact , to assure the lector the easily possible truth .

We espouse a rigid editorial insurance and we have a zero - tolerance insurance policy regarding any level of plagiarism . Our articles are resourced from reputable on-line pages . This article may hold back scientific references . The act in the parenthesis ( 1 , 2 , 3 ) are clickable links to peer - look back scientific papers .

The feedback connectedness “ Was this clause Helpful ” on this page can be used to cover content that is not exact , up - to - appointment or confutative in any manner .

This clause does not provide medical advice .

Orthostatic hypotension is the condition in which there is a decrement in blood pressure one the person seek to change military strength to the stand status in a scant period of time . Although it can be due to various medical conditions it can also come from the intake of various drug too .

Which Drugs Cause Orthostatic Hypotension?

The most vulgar group of drug to cause orthostatic hypotension is antihypertensives . It consist of beta - blockers , Alpha - blockers , atomic number 20 channel blockers , loop diuretics , thiazide diuretics , alpha + beta - blocker , vasodilator , etc . These all are the drugs that avail in reducing the profligate pressure if the patient role is hypertensive . But the overdose or the first dose of these drug could cut back the blood atmospheric pressure more than required .

Alpha - blockers are the most vulgar drug to make orthostatic hypotension in the first dot whereas beta - blockers are the commonest to be known to cause falls in blood pressure with the variety of posture also have intercourse as postural hypotension . Any diuretics be it the loop diuretic drug or the thiazidediureticthey stimulate the orthostatic hypotension by decrease the blood volume in the torso because they increase the urine production by prevent reabsorption of water from the kidney . atomic number 20 canal blockers boil down the brawn tone of the big vessels , as well as cardiac end product , is also pretend as they also have legal action on the workings of the heart resulting in the same effect on blood pressing .

Another cardiovascular grouping of drugs like Dopastat agonist , antianginals , antiarrhythmic drug , can also head to orthostatic hypotension even when they do not belong to the antihypertensive group of drugs.(1)The drug commonly used in psychiatrical illnesses are also one of the major groups causing features of orthostatic hypotension for exampleantipsychoticslike phenothiazines , antidepressant like monoamine oxidase inhibitor , selectiveserotonin reuptakeinhibitors , antidepressants , etc .

Another group of drug know as phosphodiesterase inhibitors also function similarly as that of vasodilators because they also cause dilation of the vessel which leads to the pooling of the stock and causes to fall in the line pressure when a person seek to stand . The change is sometimes so stark that the mortal hang immediately stimulate syncope .

Can Obesity Cause Orthostatic Hypotension?

While asking for a question that obesity can also cause orthostatic hypotension , the answer is yes . Orthostatic hypotension occurs inoverweightpatients by the following mechanism . When an corpulent patient is lying down , there is increase insistency on the deficient vena cava due to the weight of subcutaneous fat on the abdomen . This pressure leads to compression of inferior vena cava and there is reduced flow of descent through it stimulate what is known as venous pooling of roue . When the person strain to fend suddenly , there is a speedy fall in venous return , in turn , leads to dilute cardiac output which may or may not is compensated by an increase in meat pace but the blood pressure level come down for sure . However , this phenomenon occurs only when there is diseased corpulency that is when soundbox mass index is above 35 or 40 .

But harmonise to various studies , orthostatic hypotension is more commonly associate with lowerBMIthat is less than 18.5 which is normal.(2)The persons with body mass index on the lower side that is underweight persons are ordinarily associated with down regulation of sympathetic as well as parasympathetic nervous scheme . It leads to a decrease in the response by the consistency against the alteration in military strength and forces acting upon the stock in a downward direction . The blood vessels are not able to keep their spirit and lead to line of descent collection and in turn , ultimately get fall in the blood line pressure .

Conclusion

There are various drugs as described above which can cause orthostatic hypotension and patients should be very careful while using these drugs and should confabulate the doctor if such symptoms look . fleshiness can also be one of the causes for orthostatic hypotension .

denotation :

Also register :